Domesday Book, winner of last season's Fulke Walwyn Kim Muir Challenge Cup, is unlikely to return to action until the second half of the season after meeting with a setback.
Trainer Stuart Edmunds is eyeing a March reappearance for the seven-year-old after he sustained a tendon injury shortly after his Cheltenham Festival victory.
He said: "Domesday Book is good but he picked up a slight tendon injury. He is back in work and has been on the walker for the last few weeks, but we won't see him again until March."
He went on: "We will probably try to aim him at the same race he won at Cheltenham, then we might have a look at either the Grand National or the Irish National."
Edmunds has identified the Grade Two Mares' Novices' Hurdle Finale at Newbury in March as the long-term target for Maria's Benefit.
The five-year-old, who finished down the field in a Grade Two bumper at Aintree in April, gained her first win over hurdles at Newton Abbot on Friday.
He added: "We think Maria's Benefit is a very nice mare and she might go to Newbury for a mares' novice race in a few weeks.
"She has come out of that race at Newton Abbot fine. She had a really good blow after her first run over hurdles at Worcester and I was fairly conscious not to overdo her.
"We do like her a lot and at the end of the season we will probably try to go for the mares' novice finale at Newbury."