By Racinguk.com staff
O'Brien fields four of the 12 runners as he goes in search of a 26th Group One winner of the year, which will be a new world record.
Hydrangea's victory on Champions Day at Ascot moved O'Brien level with the late Bobby Frankel, but this is his last chance to do it in Britain, with two Group Ones in France 24 hours later before attentions switch further afield.
It has not been a bad season for Meade, though, far from it, with Aclaim providing him with a first Group One success and Eminent winning the Craven Stakes, a Group Two in France and going close in the Derby.
However, Meade is realistic his Haydock Listed winner, a general 12-1, needs to take a big leap forward up against the two ante-post favourites for the Derby in the shape of The Pentagon and Saxon Warrior, not to mention Jim Bolger's Verbal Dexterity.
"My thinking two months ago was that this would be the perfect race for him as it can cut up and is usually run on bad ground, but it's just our luck this year looks a very good race," said Meade, whose mount will have the assistance in the saddle of Andrea Atzeni, who has won the last four renewals.
"Aidan O'Brien has two of the favourites for the Derby and Jim Bolger's horse deserves the utmost respect as a Group One winner, but we can't be frightened off.
"Ours is an improving horse and he's strengthened up since Haydock, but he hasn't been tested in Group company. It would be too much to dream about winning another Group One, but hopefully he'll be thereabouts."
Joining The Pentagon, who is 5-1 with Betfaiur and Paddy Power, and Saxon Warrior, the general 7-4 favourite, for O'Brien are Dewhurst Stakes third Seahenge, a general 12-1, and Coat Of Arms, a 66-1 chance.
Heading the home team is John Gosden's unbeaten Roaring Lion, a 6-1 chance who will aim to cap an amazing autumn for the trainer after big-race wins for Enable and Cracksman.
Charlie Appleby supplemented the once-raced Loxley, while Sir Michael Stoute's Gabr, David Elsworth's Merlin Magic, Alfa Maguire from Bryan Smart's yard and Bolger's Theobald complete the list.