Unowhatimeanharry is due to put his long unbeaten run on the line in the galliardhomes.com Cleeve Hurdle at Cheltenham on Saturday.
The nine-year-old has won seven on the bounce, including the Albert Bartlett in March and the Long Walk Hurdle last month, since joining Harry Fry.
Fry has also entered Whataknight, who has been novice chasing so far this term.
There are two former winners of the Grade Two among the 15-strong entry in Reve De Sivola (2013) and the 14-year-old Knockara Beau (2014).
The latter is set to run in this race for a fifth time, having also finished second once and fourth twice.
"He's very well," said his trainer George Charlton.
"He had a race at Carlisle and was third when he was carrying 13lb more than the winner (Milborough) and a stone more than the second.
"He's well in himself. He likes Cheltenham better than Carlisle, so we're going to go there.
"If he gets into a place that would be good."
Warren Greatrex has entered Cole Harden, winner of the 2015 Stayers' Hurdle - or World Hurdle, as it was then - and Shantou Bob.
"Shantou Bob heads to the Cleeve as long as there is rain this week," the Lambourn trainer told www.wgreatrexracing.com.
"I would like to see at what level he is at - he may wear cheekpieces.
"Cole Harden could go there if the ground dries up but only if the ground is good.If it is soft he will run in a novice chase at Doncaster on Friday."
Ballyoptic, who fell at the final flight when just headed by Unowhatimeanharry in the Long Walk, has been put in by trainer Nigel Twiston-Davies, while Paul Nicholls could be double-handed with Ptit Zig and Old Guard.
Completing the list are Henri Parry Morgan, Kotkikova, The Romford Pele, The Young Master, Un Temps Pour Tout and West Approach.