Happy Like A Fool will bid to bounce back from her expensive defeat at Royal Ascot in the Bombay Sapphire Molecomb Stakes at Goodwood.
The American challenger was considered by trainer Wesley Ward as one of his best chances of a winner at this year's showpiece fixture.
Ward enjoyed a couple of winners in Berkshire, with Lady Aurelia landing the King's Stand and Con Te Partiro causing an upset in the Sandringham Handicap, but odds-on shot Happy Like A Fool had to make do with the runner-up spot behind Heartache in the Queen Mary Stakes.
The daughter of Distorted Humor has remained in Britain since, along with two stablemates, and will be Ward's first runner on the Sussex Downs when she contests Wednesday's Group Three contest.
Ward said: "After Ascot we decided to leave Happy Like A Fool at the English National Stud as Goodwood comes up so quick we felt there was no sense in bringing her home.
"She stayed there along with two other fillies, Elizabeth Darcy and Nootka Sound. Elizabeth Darcy has been to France and finished second in a Group Three and Nootka Sound could go to York next month.
"My head lad of 27 years is over there with them and everything has gone tremendously well.
"Happy Like A Fool has been working really good week in, week out.
"We've got Ryan Moore booked, I'll be there hopefully and we're all set."