John Gosden's filly was an impressive winner of the Oaks at Epsom and followed up in scintillating style in the Irish equivalent at the Curragh a fortnight ago.
Gosden also runs Jack Hobbs, an easy winner of the Sheema Classic in Dubai before disappointing on fast ground at Royal Ascot in the Prince of Wales's Stakes, while stablemate Maverick Wave is expected to employ pacemaking duties.
The Prince of Wales's Stakes was won by the admirable Highland Reel. Aidan O'Brien's five-year-old has won six times at the highest level overall and defends his King George crown.
The Ballydoyle handler also saddles Highland Reel's brother Idaho, another Royal Ascot winner in the Hardwicke Stakes.
Sir Michael Stoute's Eclipse winner Ulysses steps back up in trip to a mile and a half.
A third winner from Ascot's big meeting in June taking part is Saeed bin Suroor's Benbatl, who was fifth in the Derby before winning the Hampton Court Stakes.
David Simcock runs Eclipse third Desert Encounter, while the in-form Clive Cox is represented by My Dream Boat, fourth in the Grand Prix de Saint-Cloud when last seen.
International interests are catered for by the South American challenger Sixties Song, ridden by Gerald Mosse.
Those not declared include the Charlie Appleby-trained pair of Hawksbill and Frontiersman, Mark Johnston's Dante and King Edward VII hero Permian and Algometer from Simcock's yard.